Sr. Principle Scientist - CPAD

Posted:
12/26/2024, 1:23:37 PM

Location(s):
Chennai, Tamil Nadu, India ⋅ Tamil Nadu, India

Experience Level(s):
Senior

Field(s):
Product

  • State of the art knowledge of process chemistry, analytical chemistry, scale-up, modern synthetic methodology, including aspects of asymmetric synthesis, green chemistry, catalysis, and physical organic chemistry as it relates to reaction mechanism is expected.
  • Contemporary knowledge of drug development, the pharmaceutical industry, and fundamental principles of process development from a laboratory and manufacturing perspective.
  • Strong track record of managing integrated synthetic chemistry development laboratories with 15-30 process chemists and analytical chemists.
  • Strong track record of successful delivery of projects, using sound scientific analysis and judgment to advance programs.
  • Good interpersonal skills
  • Experience of leading and developing teams, mentoring and directing other colleagues.
  • Excellent oral and written communication skills, including the ability to maintain an accurate scientific notebook, and draft concise emails, written reports, publications, synthesis information packages and related documents
  • Rational, innovative and creative approach to problem solving. 
  • Capable of leading and planning the scientific direction of multi-discipline projects. 
  • Job location: Onsite, Chennai

  • Lead a group of 15-30 process and analytical chemists at an external partner located in India to deliver phase-appropriate processes, analytical methods and vendor synthetic information packages (VSIPs) for Pfizer’s Drug-Linker portfolio.
  • Work with Pfizer and external partner’s EHSS groups to develop and implement best practices for the synthesis, purification and handling of low OEL compounds.
  • Use extensive technical knowledge and experience in state-of-the-art organic and process chemistry to personally deliver and lead others in the development of safe, sustainable, robust, cost-efficient and phase-appropriate process that are aligned with internal business needs.
  • Develop, refine, and maintain productivity metrics of FTEs for resource allocation discussions with key internal stakeholders.
  • Develop strategic plans to drive improvement in lab capabilities (process chemistry and analytical chemistry) and enhance productivity.
  • Develop secure and robust data sharing infrastructure between Pfizer and external partners in collaboration with IT and functional areas
  • Set up business workflows to streamline material shipment and logistics
  • Build a safe, inclusive, and innovative culture within the chemistry labs.
  • Work collaboratively and effectively, building and leading high performing teams
  • Ensure accurate and timely documentation of experimental work, and clear and concise presentation of work to stakeholders both internally and externally.
  • Develop a strong relationship with external partner management, with open and effective communication and active listening (inc. sharing of plans, co-ordination of resources, alignment of priorities).
  • Build a strong interface and network with Pfizer’s Chemical Process and Analytical Development group (Global Chemical Research and Development) and keep up to date with synthetic and technology advancements.
  • Look for opportunities to align, share and implement best practices across sites.

  •  Master’s degree in Chemistry, Chemical Engineering or a related field and 15+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals

or

  • PhD in Organic Chemistry, API, Chemical synthesis or a related field with 8+ years of experience in process chemistry research and development towards New Chemical Entities (APIs) or fine chemicals
  • Experience in leading cross-functional teams is a plus.

  
Work Location : Onsite, Chennai Pfizer Site

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

Research and Development

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Pfizer

Website: https://www.pfizer.com/

Headquarter Location: New York, New York, United States

Employee Count: 10001+

Year Founded: 1849

IPO Status: Public

Last Funding Type: Post-IPO Debt

Industries: Biotechnology ⋅ Health Care ⋅ Medical ⋅ Pharmaceutical ⋅ Precision Medicine