The Opportunity:

As the Senior Associate / Manager, CMC Operations, you will play a key role in supporting CMC financial and operational activities across Relay Tx’s development programs. In this highly cross-functional role, you will partner closely with internal technical leads and external manufacturing partners to ensure the timely, compliant, and efficient delivery of clinical materials and associated documentation by providing all necessary support to the Pharmaceutical Development Team.

The ideal candidate brings strong project management and operational execution skills, have some experience in a clinical-stage biotech environment, and the ability to navigate complex, cross-functional deliverables.  This position reports to the Sr. Director, CMC Operations.

Your Role:

Financial Support & Budget Management

• Collaborate with CMC, Accounting, and Finance teams to support the creation and maintenance of department budgets and forecasts.
• Generate and finalize all departmental Purchase Orders (POs) within the Coupa system; track progress to ensure timely approval.
• Confirm that all PO requests are accurately captured in the budget; escalate and obtain approval for any items not previously included.
• Ensure contracts contain appropriate legal language, milestones, and payment terms.
• Track CMC operational expenses against budget by conducting monthly reviews of accruals in partnership with CMC functional leads (Drug Substance, Drug Product, Analytical Development, Quality, and Clinical Supply) and Finance.

Vendor and Contract Management

• Support the onboarding of new CMC and supply chain vendors.
• Meet with vendors monthly (or as needed) to monitor spending against approved contracts.
• Coordinate internal and external vendor communications and action items, including contract and PO management, budget and accrual oversight, material transfers, and inventory system support.

Operational & Program Support

• Support the execution of CMC activities across Drug Substance, Drug Product, Analytical Development/Manufacturing, and Clinical Supply Chain, including scheduling and project management tasks.
• Assist in the development and alignment of CMC project plans, risk assessments, and timelines with overall program goals; ensure timely communication of project status, timeline changes, cost updates, and risks to team members and functional leaders.
• Facilitate internal CMC team meetings, track action items, and maintain documentation to drive operational excellence.
• Contribute to continuous improvement efforts across CMC processes, tools, and data management systems.

Your Background:

Education

• Bachelor’s degree in life sciences, engineering, business, or a related field required.

Experience

• 3 to 5 years of experience in CMC operations, technical operations, or pharmaceutical manufacturing within a biotech or pharmaceutical company.
• Experience supporting clinical-stage programs and working with CDMOs.
• Working knowledge of GMP, ICH guidelines, and regulatory expectations for CMC development.

Skills & Attributes

• Strong project management, organizational, and communication skills.
• Detail-oriented and proactive, with the ability to anticipate and resolve issues.
• Collaborative mindset with the ability to work effectively within cross-functional teams.
• Comfortable operating in a dynamic environment with evolving priorities.

Estimated Salary Range: [$101,000 - $145,000].

The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.

 

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