Advancing medicine to save lives. Together.
Thanks to many decades of experience and our passion for what we do, we make an essential contribution to the global availability of biopharmaceuticals, especially for patients with rare and serious diseases.
Rentschler Biopharma SE is a leading contract development and manufacturing organization (CDMO) focused exclusively on client projects. We offer customized full-service solutions for bioprocess development and the production of complex biopharmaceuticals. As a German family-owned company with an international footprint and global reach, we combine experts, expertise and years of experience to develop best-in-class solutions – together with our clients.
Rentschler Biopharma has approximately 1,400 employees and is headquartered in Laupheim, Germany, with a site in Milford, MA, USA. In 2024, we joined the United Nations Global Compact, underlining our commitment to sustainability.
As an independent family-owned company, we live by the motto: Many hands, many minds - ONE TEAM! Open, respectful cooperation characterizes our working environment, where quality awareness, diligence and responsibility are our top priorities. With all the diversity of our talents in the Rentschler team, we pursue one vision together: advancing medicine to save lives.
Duties and Responsibilities
- Assist in the development of scale-able and robust downstream processes including process characterization, and/or technology transfer leading to clinical and commercial GMP manufacturing for multiple client projects meeting the project deliverables
- Help design experiments related to development, optimization, viral clearance, and scale-up of all steps in a recombinant protein purification process
- Independently execute chromatography and filtration experiments related to development, optimization, and viral clearance studies.
- Utilize excel and other more advanced software (JMP, MODDE) to generate graphs for process and analytical data
- Identify, evaluate, and implement new and existing technologies to improve process efficiency, control, and understanding
- Ability to work in a team environment
- Author high-quality documents, including SOPs and experimental protocols
- Serve as PD representative and participate in cross functional meetings
- Contribute to scale up activities and tech transfer related activities
- Contribute to the overall operations of the Process Sciences lab and infrastructure improvements
Qualifications
- Years of Experience (one of the following):
- A university degree and 3+ years of related experience
- A Master’s degree and 1+ years
- Basic understanding of theoretical knowledge and hands-on experience in protein purification and analytical characterization
- Hands-on experience with purification unit operations including filtration, different mode chromatography, UF/DF, AKTA, Unicorn
- Ability to author Unicorn methods for lab scale AKTA systems is preferred
- The candidate should be self-motivated, accountable, inquisitive, and have excellent organization and communication skills
- Advanced ability with Microsoft Office (Word, Excel, and PowerPoint)
- Demonstrates ability to work both independently and as a member of local / global teams
- Flexibility to switch between projects
Working Conditions
- Laboratory environment working with chemical reagents and analytical equipment
- Personal Protective Equipment must be worn as required
- Will interact with other people
- Pace may be fast and job completion demands may be high
- Normal office working conditions: computer, files, copier
Physical Requirements
- Frequent lifting up to 10 lbs
- Frequent standing/walking to work in lab environment for extended periods
- Frequent sitting for extended periods to use computer