Flatiron Research Fellow

Posted:
9/11/2025, 12:23:50 AM

Location(s):
City of Watervliet, New York, United States ⋅ New York, United States

Experience Level(s):
Senior

Field(s):
AI & Machine Learning

ORGANIZATIONAL OVERVIEW

The Center for Computational Biology (CCB) of the Simons Foundation’s Flatiron Institute is actively seeking enthusiastic, full-time post-doctoral Flatiron Research Fellows to join its Structural and Molecular Biophysics group.

The Structural and Molecular Biophysics team, a collaborative effort between CCB and the Center for Computational Mathematics (CCM)  uses computational tools to study biological macromolecules, running long timescale molecular simulations and developing statistical analysis and machine learning tools to better capture the dynamics of these molecules and understand their biological function. Areas of interest include in particular statistical mechanics, membrane protein structural biology, protein modeling with flexibility, cryo-electron microscopy, thermodynamics, modeling the effect of mutations, and intrinsically disordered proteins.  Applicants with backgrounds in mathematics, statistics, structural biology, computational chemistry, biochemistry, biophysics, or computer science are especially encouraged to apply. We are further interested in those with backgrounds in software development with skills related to methods development in cryo-EM or molecular dynamics simulation or machine learning in the context of computer vision and 3D reconstruction.

POSITION SUMMARY

Flatiron Research Fellows in CCB are individuals at the postdoctoral level with backgrounds in one or more of the following areas: applied mathematics, statistics, computational biology, biophysics, computer science, engineering, mathematical physics, or related disciplines. Reporting to Research Scientists, Data Scientists or the Center Director, as appropriate, Fellows are expected to carry out an active research program that can be independently directed and/or involve substantial collaboration with other members of CCB or the Flatiron Institute. In addition to their research, Fellows help build the rich scientific community at CCB and the Flatiron Institute by participating in seminars, colloquia, and group meetings; developing their software, mathematical and computational expertise through internal education opportunities; and sharing their knowledge through scientific publications, presentations, and/or software releases, with the financial support of the Institute. Fellows have access to the Flatiron Institute’s powerful scientific computing resources. 

Responsibilities include but are not limited to:

  • Performing theoretical and computational research

  • Developing, implementing and maintaining scientific software

  • Participating in the organization of CCB and Flatiron-wide collaborative activities including seminars, workshops and meetings

  • Participating in the preparation of manuscripts for publication and of presentations at scientific conferences

  • Assisting in student mentorship

  • Sharing expertise and providing training and guidance to CCB staff and visitors as needed.

COMPENSATION AND BENEFITS

The full-time annual compensation for this position is $91,000.

In addition to competitive salaries, the Simons Foundation provides employees with an outstanding benefits package.

FRF positions are generally two-year appointments that can be renewed for a third year, contingent on performance. Fellows will be based, and have a principal office or workspace, at the Simons Foundation’s offices in New York City.  Fellows may also be eligible for subsidized housing within walking distance of the Flatiron Institute.

For more information about careers at the Flatiron Institute, please visit simonsfoundation.org/flatiron/careers. 

Our Commitment to Expanding Pathways to Science & Opportunities for All:

Many of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds, and experiences. The Simons Foundation is committed to advancing basic science and mathematics to benefit humankind and expand our collective understanding of our world. As part of our mission, we support partners, programs, and initiatives that seek to broaden the scientific community and open pathways to science and mathematics careers.

The Simons Foundation provides equal opportunities to all applicants without regard to race, religion, color, age, sex, pregnancy, national origin, sexual orientation, gender identity, genetic disposition, neurodiversity, disability, veteran status, or any other protected category under federal, state, and local law. #LI-DNI