Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

Uncover a remarkable opportunity at Thermo Fisher Scientific Inc. to push global advancements in health, cleanliness, and safety as a Sr. IT Program Manager in Waltham. Become a part of our elite team, guiding ambitious IT projects that enhance quality, compliance, and supply chain operations within our Contract Development and Manufacturing Organization (CDMO).

Argument Development & Case Creation

• Collaborate with business leaders to determine opportunities where technology provides measurable business value.
• Develop and present cases justifying investments by outlining the value, benefits, and resource requirements.
• Translate strategic goals into actionable IT roadmaps that support growth, scalability, and regulatory compliance.
• Support portfolio governance and prioritization discussions through data-driven analysis.

Financial Oversight

• Manage program budgets, forecasts, and capital/operating expense planning.
• Monitor and report financial performance, ensuring accountability and transparency.
• Identify cost optimization and efficiency opportunities within vendor and system portfolios.
• Provide variance analysis and investment recommendations to senior leadership.

Vendor & Partner Management

• Lead the selection, contracting, and performance oversight of technology vendors and service providers.
• Negotiate statements of work (SOWs) and service-level agreements (SLAs) in collaboration with Procurement and Legal.
• Monitor vendor delivery, quality, and compliance performance against expectations.
• Champion positive relationships that drive innovation and operational excellence.

Quality, Compliance & Inspection Readiness

• Ensure all IT programs meet global regulatory and validation standards (21 CFR Part 11, GxP, GAMP 5, EU Annex 11).
• Maintain ongoing inspection readiness by ensuring complete validation documentation and traceability.
• Partner with Quality and Compliance teams to prepare for internal and external audits.
• Represent IT during inspections and drive timely remediation where vital.

Systems & Integration

• Manage the incorporation and enhancement of essential platforms like ERP, MES, QMS, LIMS, and SCM systems.
• Ensure system development aligns with data integrity, cybersecurity, and infrastructure standards.
• Collaborate with architects and functional leaders to enable process harmonization and scalability.

Experience

• 5+ years of proven experience leading IT projects within the life sciences, biotech, or pharmaceutical manufacturing industry (Preference for CDMO experience).
• Demonstrated success leading large, complex, cross-functional technology initiatives.
• Strong understanding of Quality, Regulatory, and Supply Chain business procedures.
• Experience developing and leading program budgets and justifications.
• Proven success leading vendors and third-party service providers.
• Practical familiarity with ERP, MES, QMS, LIMS, or Supply Chain systems.
• Solid understanding of GxP and data integrity requirements.
• Strong leadership, influencing, and collaboration skills.
• Excellent communication and presentation abilities with executive audiences.
• Ability to lead multiple initiatives in a fast-paced, regulated environment.
• Certifications such as PMP, ITIL, or Agile Scrum Master preferred.

Compensation and Benefits

The salary range estimated for this position based in Massachusetts is $143,000.00–$214,475.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs

• Employee assistance and family support programs, including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards