Posted:
2/22/2026, 3:07:13 PM
Location(s):
California, United States ⋅ Pasadena, California, United States
Experience Level(s):
Expert or higher ⋅ Senior
Field(s):
Operations & Logistics ⋅ Sales & Account Management
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Let’s do something amazing together! The Director of Sales Operations will play a pivotal role in the commercial success of Arrowhead’s leading investigational cardiometabolic medicine – Redemplo (siRNA targeting APOC3). This product has demonstrated compelling clinical data to date, has been approved by the FDA for Familial Chylomicronemia Syndrome (FCS) and is in late-stage development for the treatment of other grievous conditions, including Severe Hypertriglyceridemia (SHTG). Over time, the role will expand to cover additional indications and products in the Arrowhead portfolio.
In this key position, you will be leading Sales Operations for our field-based teams. Reporting directly to the Head of Commercial Operations and working closely with Head of Sales and Head of Marketing, you will play a crucial role in the execution of commercial strategy. Specifically, you will translate commercial objectives into plan-of-action and goals for the field-based teams, you will ensure proper sizing, targeting and incentive compensation. You will also help optimize systems (CRM) and logistics (fleet) support for the field.
This role is based in Pasadena, California, with an expectation to be in office 5 days a week.
Responsibilities
Requirements
Preferred
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
Website: https://arrowheadpharma.com/
Headquarter Location: Pasadena, California, United States
Employee Count: 251-500
Year Founded: 1989
IPO Status: Public
Last Funding Type: Post-IPO Equity
Industries: Biotechnology ⋅ Health Care ⋅ Nanotechnology ⋅ Pharmaceutical