Scheduled Hours
40
Position Summary
The Prabhu laboratory focuses on understanding the role of inflammation and the immune system in heart failure. The lab has uncovered evidence for broad immune dysregulation in heart failure that contributes to tissue injury and pathological cardiac remodeling, and ultimately to disease progression. These abnormalities encompass both the innate and adaptive immune systems and specific signaling pathways within immune cells. The laboratory uses animal models of both genetic and acquired heart failure to investigate mechanisms of disease. This requires the use of cardiac surgery, echocardiographic imaging, and hemodynamic assessment in mice, and the use of flow cytometric, histopathological, biochemical, and molecular approaches. We hope to use these findings to develop new immunomodulatory therapeutic strategies in experimental heart failure, with translation and correlation to human disease.
Job Description
Working Conditions
A laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment, provide standard care to research animals, and handle human biosamples.
Salary Range
Base pay is commensurate with experience.
Preferred Qualifications
- Experience working with mice, including husbandry and genotyping.
- Experience with molecular biology and biochemical techniques.
- Experience with microscopy (confocal, dissection, compound, EM).
- Working knowledge of computer software (Excel, Photoshop, and Prism) and general lab equipment.
- Demonstrated ability to work independently and communicate effectively.
- Troubleshooting skills.
- Ability to maintain complete and organized records.
- Effective verbal, written and interpersonal communication skills.
Required Qualifications
Candidates with prior experience in physiology, molecular biology, biochemistry, and/or cell biology with at least a bachelor’s degree are encouraged to apply.
Grade
00
Questions
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Accommodation
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Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
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Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.