Job Description

Field of Study: Metabolism, Inflammation, Immunology, Molecular Biology.

This position seeks to elucidate the cellular and molecular mechanisms of inflammatory osteolysis and metabolic regulation of skeletal/joint homeostasis and pathology. The approaches include the development and use of genetically engineered mice as disease models of inflammatory bone lysis and joint diseases to mimic human bone and joint pathologies.

The candidate will work closely with the principal investigator to outline research goals, review relevant literature, design research protocols independently based on methods in the literature related to research project, including developing procedures for the data collection, verification and management of project. The candidate will also present data at meetings, and assists with grant preparation and publication of results. The candidate will participate in routine daily functions of the laboratory as a team player.

Required Qualifications

• Doctorate degree (M.D. and/or Ph.D.).
• Basic experience in research lab operations and relevant training in cell and molecular biology, preferably related to immunology, inflammation and bone.
• Highly motivated, organized, reliable, and career-driven.
• Demonstrated ability to perform well in a research laboratory setting, to work independently and communicate effectively.
• Troubleshooting skills, an ability to maintain complete and organized records, and a working knowledge of standard computer software and general lab equipment.
• Excellent skills in cell cultures.
• Basic knowledge on mouse genetics.
• Ability to handle mice.
• Molecular biology skills (cloning, mutagenesis, transcriptional analysis, perform mouse genotyping, isolation of mRNA and analysis, plasmid and retrovirus preparation and gene transfer), protein analyses (Western blot, FACS, IHC/IF and ELISA).
• Experience with advanced protein chemistry and molecular biology, microscopy, flow cytometry, and established expertise with mice.
• Computer literacy, including the ability to use a variety of software packages to analyze data.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards.  The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience.

Applicant Special Instructions

Interested candidates should send a CV and three references to Dr. Abu-Amer at [email protected]. Applications will be reviewed until suitable candidate is identified.

Contact Name: Yousef Abu-Amer, Ph.D.
Phone: 314-362-0335
Fax: 314-362-0334
Mailing Address:
Washington University Orthopaedics
425 South Euclid Ave
St. Louis MO 63110
BJC - Institute Of Health-11627: Campus Box 8233
St. Louis, Missouri, 63110

Phone: 314-362-8597

Email address: [email protected]
Link to Website: http://www.orthoresearch.wustl.edu/content/Laboratories/2957/Yousef-Abu-Amer/Abu-Amer-Lab/Overview.aspx

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email [email protected] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO/AA Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Diversity Statement

Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.