Posted:
10/11/2024, 8:11:31 AM
Location(s):
South San Francisco, California, United States ⋅ California, United States
Experience Level(s):
Expert or higher ⋅ Senior
Field(s):
Medical, Clinical & Veterinary
Pliant Therapeutics is a late-stage biopharmaceutical company focused on the discovery and development of novel therapies for fibrotic diseases. Founded by Third Rock Ventures with world-renowned academic thought leaders, Pliant is raising the bar to meet the unmet medical needs of physicians, patients and families impacted by fibrotic diseases. As the leader in the discovery and development of novel therapeutics for the treatment of fibrotic diseases, Pliant is developing small molecule drug candidates specifically designed to impact the fibrotic process.
The Company’s lead product candidate, bexotegrast (PLN-74809), is an oral small molecule, selective inhibitor of the αvβ1 and αvβ6 integrins that play a key role in multiple fibrotic pathways. Bexotegrast has received Fast Track Designation and Orphan Drug Designation from the U.S. Food and Drug Administration for both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC) and Orphan Drug Designation from the European Medicines Agency in IPF and PSC. Pliant is currently conducting BEACON-IPF, a Phase 2b/3 trial of bexotegrast for the treatment of IPF.
Pliant is conducting a Phase 1 study for its third clinical program, PLN-101095, a small molecule, dual-selective inhibitor of αvß8 and αvß1 integrins, that is being developed for the treatment of solid tumors. The Company also has discovery and development programs in oncology and muscular dystrophies.
The Senior Director, Clinical Science Liaisons, is a key role within Pliant’s Development Operations team and will be responsible for program and team oversight, and co-developing strategic plans to provide non-promotional clinical, educational, and study support across Pliant’s development portfolio. The Senior Director, Clinical Science Liaisons, reports to the Vice President, Clinical Operations.
This is a field-base or local position (South San Francisco).
To perform this job successfully, an individual must be able to perform each essential duty. The requirements listed below are representative of the knowledge, skill, abilities, and prior experience required.
Pliant requires all new hires to be fully vaccinated prior to the first date of employment (subject to any legally required exemptions).
The annual base salary for this role is $280K – $290K. Individual pay may vary based on additional factors, including, and without limitation job-related skills, experience, work location and relevant education or training. Pliant’s compensation package also includes benefits, equity, and annual target bonus for fulltime positions.
To understand how Pliant complies with and manages your personal information with respect to the California Consumer Privacy Act, please visit https://pliantrx.com/ccpa-applicant-and-staff-privacy-notice/.
Website: https://pliantrx.com/
Headquarter Location: South San Francisco, California, United States
Employee Count: 101-250
Year Founded: 2015
IPO Status: Public
Last Funding Type: Post-IPO Equity
Industries: Biotechnology ⋅ Health Care ⋅ Health Diagnostics ⋅ Pharmaceutical ⋅ Recruiting ⋅ Therapeutics