Scientist II, In-Vivo Pharmacology

Posted:
7/24/2024, 8:32:58 AM

Location(s):
Massachusetts, United States ⋅ Boston, Massachusetts, United States

Experience Level(s):
Junior ⋅ Mid Level

Field(s):
Medical, Clinical & Veterinary

Scorpion is a pioneering clinical-stage oncology company redefining the frontier of precision medicine to deliver optimized and transformational therapies for larger populations of patients with cancer. Scorpion has built a proprietary and fully integrated platform of the most advanced technologies across cancer biology, medicinal chemistry, and data sciences, with the goal of consistently and rapidly creating exquisitely selective small molecule compounds against an unprecedented spectrum of targets. Scorpion aims to leverage its platform to advance a broad pipeline of wholly owned, optimized compounds across three target categories: best-in-class molecules targeting validated oncogene targets; first-in-class molecules for previously undruggable targets; and first-in-class molecules for novel cancer targets.

JOB SUMMARY

We are seeking a highly motivated Scientist II with a demonstrated track record of successes to join our dynamic biology drug discovery team.  This candidate will serve a critical role in conducting mouse tumor xenograft studies in support of target validation and small molecule drug discovery from early discovery to IND stage for multiple projects simultaneously.  This individual will also work seamlessly with biology, chemistry and DMPK to design experiments and conduct hands-on work in the vivarium and lab.  This position is ideal for a talented, results driven individual who will thrive in a fast-paced, innovative, start-up environment.

KEY RESPONSIBILITIES:

  • Plan and coordinate in vivo experiments in-house and externally
  • Leverage organizational and communication skills to collaborate effectively with colleagues in biology and medicinal chemistry
  • Represent pharmacology on multiple project core teams
  • Analyze and present data to project teams and department meetings
  • Maintain high-quality, detailed experimental records within the ELN
  • Design and execute PK/PD/efficacy studies

PROFESSIONAL EXPERIENCE/QUALIFICATIONS

  • PhD. in pharmacology, biology or a related field
  • 2+ years of industry experience required
  • Experienced with cell culture and molecular biology techniques such as western blotting, qPCR and other plate-based assays and imaging techniques
  • Skilled in animal handling, compound formulation, dosing (PO/IV/SC/IP), basic surgery and necropsy techniques
  • Outstanding organizational, analytical and interpersonal skills
  • Ability to multi-task in a fast-paced environment while maintaining the highest quality of experimental execution/quality
  • Desire to contribute to teams working on challenging technical and scientific problems
  • A strong record of achievement, including publications

Scorpion Therapeutics Inc. is an Equal Opportunity Employer who strives to create and maintain a diverse working environment. We do not discriminate for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Beginning October 13, 2021, Scorpion Therapeutics requires all new hires to be fully vaccinated against COVID-19. If you are unable to receive the vaccine due to a disability or serious medical condition, or because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.