ROLE SUMMARY

The Sr Director, Global Medical Affairs, Lyme Disease Vaccine is responsible for designing and executing the medical strategies leading to the licensure and public health implementation of a Lyme disease vaccine currently in phase 3 clinical trials. This includes developing the evidence generation strategy, engaging external stakeholders, and collaborating with Research, Clinical, Medical Evidence Generation and Commercial/Access cross-functional teams to optimize medical benefit and support vaccine recommendations globally.

The Sr Director, Global Medical Affairs, Lyme Disease Vaccine will manage relationships and actively build networks with key opinion leaders in the infectious diseases and vaccinology field, Vaccine Technical Committees (VTCs), healthcare policy makers, and payers, to obtain strategic input and establish research partnerships. They will develop a multi-disciplinary research agenda that clearly defines the burden of disease due to Lyme disease, target age groups, risk factors, and outcomes and includes vaccine effectiveness and other post-licensure evaluations. They will collaborate with commercial and market access teams to develop appropriate, scientifically accurate marketing and access strategies, and propose medical affairs tactics to support these activities.

This is a dynamic role that requires a firm understanding of the epidemiology of vector-borne infectious diseases, vaccine preclinical and clinical development, and vaccine policy and implementation, as well as the ability to objectively interpret technical and commercial information in order to optimize clinical development, market access, and lifecycle strategies. Leadership for local licensing and VTC recommendations are also needed.

ROLE RESPONSIBILITIES

• Serves as subject matter for Lyme disease and Lyme disease vaccine
• Acts as key point of accountability for scientific inquiries and communications regarding Lyme disease. 
• Develops cross-functional multi-disciplinary research agenda including epidemiology, clinical trials, outcomes research, policy, and implementation operationalized by Medical Affairs/Medical Evidence Generation/V&E and other cross-functional colleagues, including:
  • Sets the research and data priorities, including strategies to address data gaps
  • Operationalizes evidence generation activities through exploration of research collaborations, independent research support, and Pfizer-sponsored studies.
  • Partners with Medical Evidence Generation group to develop generic study designs that will be used globally for epidemiological studies (e.g., surveillance methods; use of different diagnostic techniques; and molecular methods) and ensure implementation of epidemiology studies globally
  • Collaborates with experts in epidemiology, statistics and data analysis to analyze and interpret study data
• Ensures integration of scientific information (including epidemiology, disease burden, and public health value) in the asset strategy.
• Is responsible for proactively keeping up to date and informing the vaccines CSI and GAV cross-functional team of new clinical/scientific activities by competitors (e.g. new, relevant clinical trials disclosed in the public domain, emerging data, etc.).
• Supports Lyme disease vaccine launch team.
• Chairs the Lyme Disease Evidence Generation Subcommittee, which reviews internal and external study proposals
• Creates and operationalizes the publication strategy in partnership with internal and external research groups.
• Contributes to the scientific evidence base via publishing in peer-reviewed manuscripts and presenting at conferences.

Management and budget accountability

• No direct reports or budget accountability

BASIC QUALIFICATIONS

• MD with 8+ or more years’ experience
• Academic or comparable training in epidemiology required (MPH / MS / PhD / EIS)
• At least 8 years of medical and scientific experience in vaccines, essential.
• Able to influence and succeed through others.  Able to form excellent relationships with key global and local cross-functional partners.
• Demonstrated ability to identify key data gaps, develop an evidence generation strategy, and oversee implementation of epidemiological studies in support of clinical trial design and market access (VTC recommendations and reimbursement) globally.
• Able to review, evaluate, interpret, and present complex data; understand the emerging safety and efficacy profile of the vaccine candidates, and analyze published data and competitive intelligence to provide a comparison with standard of care and comparator vaccines.
• Excellent verbal and written communication skills including scientific writing and presentation skills and strong interpersonal skills. 
• Strong work ethic and proven track record of delivering high quality within timelines.
• Entrepreneurial and motivated to challenge dogma and the status quo.
• Innovative in identifying new opportunities and finding new ways to create value.
• Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

PREFERRED QUALIFICATIONS

• Networking – Credibility and approachability to establish and maintain important partnerships across functions.
• Accountability - for self and others - Takes personal accountability for outcomes and holds other accountable for their commitments.
• Grows Others - Actively coaches and develops others.  Provides opportunities and experiences to develop skills and competencies.
• Leads Through Change, Builds Change - Develops self and others in a way that enables a flexible and adaptable response to change. Demonstrates support for organizational and process changes.
• Teamwork – must be a strong team player.
• Self-Awareness - Recognizes own strengths and limitations and personal motivations. Actively seeks feedback and knows one’s impact on others.  Acts with authenticity and maturity.
• Insight, Influence & Inclusion - Understands other peoples’ unspoken as well as explicit concerns.  Adapts own approach and behavior to be more effective and inclusive and to have positive impact on others.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Domestic and international travel 10-25% time for internal meetings, congresses, stakeholder engagement meetings.

Work Location Assignment:  This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.

The annual base salary for this position ranges from $242,000.00 to $403,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Medical