Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)

About the Role:

The Principal Cloud and Infrastructure Engineer serves as the senior technical authority responsible for designing, modernizing, and optimizing enterprise-scale Azure-centric cloud environments integrated with AWS and on-premises infrastructure. This role drives large-scale platform transformations including workload migration, infrastructure consolidation, automation-first provisioning, cost optimization, GxP-aware cloud environments, and performance engineering across hybrid architectures. The position requires deep expertise in Azure cloud engineering, strong AWS experience, and hands-on integration with VMware virtualization, enterprise storage, identity systems (AD/Azure AD), networking, and scientific compute platforms. The Principal Engineer defines platform strategy, establishes architectural standards, leads complex cross-functional programs, and ensures secure, compliant, highly available, and cost-efficient operations across the enterprise.

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Your Contributions (include, but are not limited to):

• Lead large-scale technology infrastructure consolidation, virtualization, and cloud migration initiatives.

• Drive automation-first engineering using Infrastructure as Code (Terraform, ARM/Bicep, CloudFormation) across cloud and on-prem environments.

• Design and implement API-driven, self-service provisioning platforms integrated with ServiceNow and identity systems.

• Lead cloud cost optimization and FinOps initiatives across Azure and AWS, including savings strategies and governance controls.

• Architect and optimize VMware platforms with high availability, disaster recovery, and footprint reduction strategies.

• Design scalable storage architectures across Azure, AWS (S3, FSx), and on-prem NetApp with automated tiering and lifecycle management.

• Enable secure, on-demand compute platforms supporting containerized workloads (Docker/Kubernetes) and advanced analytics use cases.

• Implement identity-driven access models using AD/Azure AD with policy-based provisioning and role-based controls.

• Design and implement hybrid connectivity models including ExpressRoute, VPN, SD-WAN, private endpoints, and secure access solutions.

• Integrate security, compliance, and regulatory best practices (including GxP-aware environments) into hybrid architectures.

• Build enterprise observability frameworks including performance, reliability, utilization, and cost dashboards to drive operational excellence.

Requirements:

• Bachelor's degree in Computer Science, Information Technology, or related field and 6+ years of infrastructure engineering experience with 4+ years focused on AWS

• Master's degree in Computer Science, Information Technology, or related field and 4+ years of experience as listed above

• High School Diploma, GED, or equivalent and 10+ years of equivalent experience, training, or certifications

• Certifications such as Azure Solutions Architect Expert , Azure DevOps Engineer Expert or similar

• Experience supporting GxP-regulated environments

• Experience supporting scientific computing / bioinformatics workloads

• Experience with container-based platforms (Docker, Kubernetes)

• Experience building self-service automation frameworks

• FinOps or cloud cost governance experience

• Azure Solutions Architect Expert (required)

• AWS Solutions Architect (preferred)

• Understands key business drivers and uses this understanding to accomplish work

• Has strong understanding of processes, procedures and systems used to accomplish the work and recognizes downstream impact on other functional areas

• Proficient with tools and processes that support work conducted by functional area

• Ability to work as part of a team; may train lower levels

• Strong communications, problem-solving, analytical thinking skills

• Detail oriented yet can see broader picture for department

• Ability to meet multiple deadlines, with a high degree of accuracy and efficiency

• Strong project management skill

​Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.