Global Commercial Director, Immunology Cell Therapy

Location: Boston, US

The Biopharmaceutical Business Unit (BBU) bridges science and commercial, integrating corporate, portfolio, therapy areas and product strategies, providing strategic direction from early-stage research through to commercialization.

Cell therapy has the potential to change the treatment paradigm of autoimmune disease, offering a new modality that may provide deep and durable response in difficult to treat, chronic diseases. AstraZeneca is establishing a portfolio of cell therapy options to address multiple autoimmune and neurology diseases, in collaboration with the oncology and rare disease business units.

Within the Global Respiratory & Immunology (R&I) Therapeutic Area, reporting to the Head of Cell Therapy, Immunology, you will help craft AZ’s future portfolio by driving commercial activities for our launch into the Cell Therapy space across multiple autoimmune diseases. You will be expected to have a high level of collaboration with global functions (e.g. R&D, Business Insight / Analytics, Finance, Medical Affairs, Pricing & Market Access) and our local Marketing Companies, in particular in the US. Close collaboration with our global oncology and rare disease business units will also be key to success.

In this role, you will be evolve the global commercial strategy for immunology cell therapy, developing critical insights to drive our approach and defining the go-to-market model. You will collaborate closely with the US leadership team as well as the Global Immunology Cell Therapy Commercial and R&D colleagues to ensure fit-for-purpose solutions are proposed, that serve both the enterprise and the US marketing company.

The successful candidate must be a very strong matrix operator, good communicator and well-rounded commercial thinker, with a specific appetite for cross functional collaboration and entering yet-to-be established commercial markets. Clear strategic thinking with the ability to lead and demonstrate passion for the brands and future technology is required, given the desire of AZ to be a future leader in cell therapy across multiple diseases and settings.

What you’ll do:

• Develop and implement winning commercial strategies for the clinical stage cell therapy asset, working with the Head of Cell Immunology Cell Therapy to ensure robust and compelling positioning and competitive differentiation based on deep market insights
• Shape pre-launch and launch plans, building clear, market-defining programs that position the brand around unmet needs
• Collaborate with Commercial Leadership and engage with Regional and Country teams to ensure strategic alignment and share best practices, delivering the global ambition
• Drive understanding of the requirements for a go-to-market strategy and customer engagement model for immunology and integration with other business units
• Continue to drive patient centricity and innovation through all aspects of immunology cell therapy strategy
• Lead commercial readiness for investment decisions in one or more LCM indication opportunities
• Contribute to BD assessments of external opportunities in cell therapy and beyond to evolve the cell therapy portfolio
• Engage with Key External Experts (KEEs) to gather input to inform the respiratory strategy and activities plan including advocacy development
• Produce future-ready revenue forecasts and business cases through rigorous customer insight and commercial judgement
• Oversee budgets and agency workflows, ensuring resources are aligned to maximize campaign impact and efficiency

Minimum Qualifications and capabilities:

• Bachelor’s degree is required in Business, Medical or Life sciences
• 10+ years of experience in pharmaceutical development and commercialization Significant and in-depth understanding of global commercial strategy, methodologies and tools (product profiling and positioning, forecasting, pricing and reimbursement, market research techniques, competitive intelligence resources)
• Experience of crafting brand strategy whilst the understanding of product profile was incomplete and evolving
• Detailed ‘hands-on’ knowledge of building TPPs, generating sales forecasts and business cases
• Thorough understanding of the drug development process and the need for commercial line of sight throughout
• Understanding of future healthcare market challenges
• Strong interpersonal and team leadership skills, demonstrating flexibility and a validated ability to deal with complexity under time pressure
• Proven strong influencing skills and stakeholder management
• Experienced and comfortable working in a matrix environment

Preferred Qualifications and capabilities:

• An advanced degree (MBA, MSc or PhD)
• Experience in immunology
• Experience in both market and global commercial organisations
• Launch experience

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial -finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what’s next!

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

The annual base pay for this position ranges from $229,303 to $343,955. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​

Compensation Pay Range:

229,303.20 - 343,954.80 USD Annual

The annual base pay (or hourly rate of compensation) for this position is outlined above. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

08-Jan-2026

Closing Date

22-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.