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Senior Scientist - Organoids

We are looking for a highly motivated scientist with experience in organoid culture and oncology cellular biology to join the Oncology Translational Research team within GSK Oncology TA. The Oncology Translational Research team will partner with Oncology TA team members to increase clinical translatability and to contribute to preclinical development programs within GSK Oncology TA.

The successful candidate will work as part of a team that, by exploiting patient-derived organoids, is developing and implementing cutting-edge cellular, genomic and molecular techniques with a multimodality analytic approach, plus machine learning models to improve cancer patient risk stratification as well as to predict future targeted and/or immuno-therapy susceptibilities.

We are looking for this role to be based in Stevenage only.

In this role you will…

• Upon reception, expansion of Patient-derived organoids alone or in coculture with other cell types (immune cells/ fibroblasts)
• Performing patient-derived organoids quality control steps (cell density, proliferation rate and cytotoxicity evaluation).
• Organoids and immune cells staining for flow cytometry analysis
• Collecting and reporting data to the lab head.
• Executing and delivering of the project.
• Collaborating/cooperating with KCL scientists within the GSK-KCL Translational Oncology Research Hub, an exclusive research collaboration between GSK and the Comprehensive Cancer Centre at KCL. 

Basic Qualifications

We are looking for professionals with these required skills to achieve our goals:

• BSc in Cell Biology/Oncology or related
• Experience in 3D cell culture techniques (patient-derived organoids)
• Cell biology related techniques (cytotoxicity analysis, cell culture, drug treatment)
• A multidisciplinary mix of training/expertise in Oncology and Cancer cell biology.
• Ability to communicate with team members from different backgrounds by training/discipline, as well as senior members of the GSK stakeholders/research partner units
• Ability to deliver high quality, consistent results in a timely fashion with a positive can-do and result oriented attitude 

Preferred Qualifications

If you have the following characteristics, it would be a plus:

• MSc or PhD in Cell Biology/Oncology or related
• Experience in flow cytometry
• Immunology background
• Molecular biology experience (Western Blot)

Closing Date for Applications: Monday 26th August 2024

Please take a copy of the Job Description, as this will not be available post closure of the advert.
 When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

GSK R&D

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery.  We are revolutionising the way we do R&D. We’re uniting science, technology and talent to get ahead of disease together.

Find out more:

Our approach to R&D.   

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

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