Principal Systems Engineer

Posted:
5/5/2026, 11:32:56 PM

Experience Level(s):
Expert or higher ⋅ Senior

Field(s):
IT & Security

Workplace Type:
Remote

When our values align, there's no limit to what we can achieve.
 
At Parexel, we all share the same goal - to improve the world's health. From clinical trials to regulatory, consulting, and market access, every clinical development solution we provide is underpinned by something special - a deep conviction in what we do.

Each of us, no matter what we do at Parexel, contributes to the development of a therapy that ultimately will benefit a patient. We take our work personally, we do it with empathy and we're committed to making a difference.

Seeking a motivated Principal Systems Engineer – M365 to join our global team. This role is responsible for the strategy, adoption, and operational management of the Microsoft 365 platform, with a strong focus on maximizing business value across the organization.

Key Accountabilities:

  • Own and optimize Microsoft 365 services (Teams, SharePoint, Exchange, OneDrive, Copilot)

  • Drive adoption of M365 Copilot and modern collaboration tools

  • Lead clear, end-user focused communication for M365 changes and updates

  • Ensure platform performance, security, and compliance

  • Partner with business and IT to deliver M365 solutions aligned to needs

  • Establish standards, documentation, and best practices

  • Act as escalation point for complex issues and mentor team members

  • Track usage and adoption to drive continuous improvement

Skills:

  • Strong communication and ability to simplify technical concepts

  • Proven ability to drive adoption and change at scale

  • Strong stakeholder management and problem-solving skills

  • Ability to operate in a fast-paced environment

Knowledge and Experience:

  • Deep experience with Microsoft 365 platform

  • Hands-on experience with M365 Copilot or similar tools

  • Experience driving enterprise adoption initiatives

  • Strong understanding of M365 security and governance

  • 8–10+ years in large, global environments

Education:

  • B.A. or B.S. in Computer Science or equivalent experience

  • Relevant Microsoft certifications preferred

Parexel

Website: https://www.parexel.com/

Headquarter Location: Waltham, Massachusetts, United States

Employee Count: 10001+

Year Founded: 1982

IPO Status: Delisted

Last Funding Type: Venture - Series Unknown

Industries: Biopharma ⋅ Biotechnology ⋅ Consulting ⋅ Industrial ⋅ Medical Device ⋅ Web Development