Immunopeptidomics Scientist

Posted:
11/3/2024, 10:50:58 PM

Location(s):
Massachusetts, United States ⋅ Watertown, Massachusetts, United States

Experience Level(s):
Mid Level ⋅ Senior

Field(s):
Data & Analytics

Workplace Type:
On-site

Parallel Squared Technology Institute (PTI) is a non-profit research institute aiming to catalyze a leap in protein analysis technology and use it to explore new biological frontiers. PTI supports open research and educational opportunities supporting rapid career development for scientists, engineers, and mathematicians.

Why? Protein dysfunctions directly cause many diseases, such as Alzheimer’s disease. Yet, proteins remain understudied because of technological hurdles.

How? To resolve these limitations, PTI will develop mass tags enabling a new framework for multiplexed protein analysis by mass spectrometry towards achieving 100-fold increase in throughput. Scientists at and collaborating with the institute will use these gains to directly investigate disease mechanisms and resolve problems that have proven intractable for decades. Our proof of principle technology and strategies are outlined at: parallelsq.org.

New career opportunities
Members of PTI will be supported with industry-level resources to lead research projects and disseminate their discoveries and innovations to the broader biomedical community through frequent publications, presentations, and submissions to public data portals.  

Summary of Position
We are looking for an Immunopeptidomics Scientist who has done research in the field of mass spectrometry-based proteomics. This position will focus on using bulk and single-cell analysis to increase the throughput of HLA and/or MHC peptide identification. The idea candidate has an in-depth understanding of instrumentation in addition to sample processing and data analysis. In this role, the successful applicant will have the opportunity to work closely with co-founders and an interdisciplinary group of researchers to help achieve PTI’s milestones.  In order to be seriously considered for this position, we require a cover letter as part of the candidate’s application.
We aim to help fill a structural gap in today's R&D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.
 
We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.