Research Opportunities (Sarcoma Cancer Research) - Medical Oncology

Posted:
7/1/2024, 5:00:00 PM

Location(s):
St. Louis, Missouri, United States ⋅ Missouri, United States

Experience Level(s):
Junior ⋅ Mid Level ⋅ Senior

Field(s):
Medical, Clinical & Veterinary

Scheduled Hours

40

Position Summary

Sarcomas are a rare group of over 80 types of tumors of mesenchymal origin that can be divided
into 2 categories: soft tissue sarcomas (STS) and bone sarcomas. In 2018, the incidence of all
sarcomas was 15,000 patients, of which soft tissue sarcomas represented 80%. For high grade
non-metastatic soft tissue sarcomas, the standard of care treatment involves surgical excision,
chemotherapy, and adjuvant radiation. Despite this multimodality approach, the risk of relapse
remains high at 50%, with most of these representing metastatic failures. Identification of better
systemic treatments to prevent relapse are needed.

Our lab focus on the understanding of tumor metabolism, metabolism-tumor microenvironment
interactions, and mechanisms of treatment escape in sarcoma. The ultimate goal of our group
is the development of new targeted therapeutics to sarcoma and the improvement of current
cancer treatments.

In our laboratory, we utilize a variety of metabolomics, transcriptomics, proteomics, and
molecular biology techniques to elucidate the underlying biology of sarcoma and identify
therapeutically actionable targets in a highly supportive and collaborative environment. In this
pursuit, we make extensive use of both mouse models and primary tissues.

Job Description

For additional information about the Van Tine Laboratory please visit our lab page at https://sites.wustl.edu/vantinelab/.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience.

Preferred Qualifications

  • A background in biology, biochemistry, microbiology or related field is highly desirable.
  • Willingness to perform mouse work is highly preferred.
  • Previous basic or translational laboratory experience is highly preferred.
  • Excellent interpersonal skills.
  • Ability to communicate effectively and work collaboratively.
  • Ability to perform, trouble shoot, and analyze experiments.
  • Excellent record keeping and organizational skills.

Required Qualifications

Bachelor’s degree.  Candidates with additional education and experience are encouraged to apply.

Grade

00

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email [email protected] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO/AA Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Diversity Statement

Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.