The VP, Global Medical Lead, IL-5 is a key senior business leadership role and member of the Global Medical Affairs, Specialty Medicines Leadership team.  This individual reports to the VP, Head of Global Medical Affairs, Specialty Medicines who is a key member of GSK’s Chief Patient Officer Leadership Team. 

The Global Medical Lead will have full responsibility for the Global Medical Strategy for both Mepolizumab and Depemokimab, both anti-IL5 monoclonal antibodies.  The Global Medical Lead will lead the translation of our science to shape the practice of medicine and deliver positive health impact for patients by providing healthcare decision-makers around the world with the evidence and confidence they need on GSK therapies, and influencing internal stakeholders with medical insight and expertise related to Development and Commercialization strategies. The role will be accountable for the medical strategic direction of an Asset or Portfolio of assets and the matrix leadership of the Global Asset Medical Leadership Team, integrating innovative strategies that advance patient care and help shape the practice of medicine.  The role will partner with key markets to ensure that their insights are used to inform all evidence, asset/vaccine development and strategic deliverables as well as partnering across Commercial and R&D to deliver value for patients.   

In addition to leading the Global Medical Team for Mepolizumab and Depemokimab, the incumbent will be a member of several additional matrix teams including the Medicines Development Team and the Medicine Commercial Team where he or she will provide Medical insight and expertise to inform and influence data generation and scientific communication plans across the lifecycle to optimize patient impact within markets.

A key focus of the role is to develop and stretch self and team to be the best in the industry at delivering impact for patients and improving patient care paradigms.

Key Responsibilities

• Lead the cross-functional global medical team and influence product development at the global level
• As chair of the global medical team
  • Jointly accountable for developing the global medical brand strategy and plans for a product by convening the global medical team
  • Set direction along strategic framework of the medical brand plan including setting scientific objectives, own the medical scientific narrative and the integrated communication plan
  • Accountable for directing and coordinating global resources to generate data and create content to support priority markets, leveraging the expertise of the Global operations team and Global data team
  • Represent medical in cross-functional strategy meetings and workshops, and proactively offer options for innovative medical strategy for the IAP at the MDT and MCT meetings
  • Provide focused support at key inflection points during development (e.g., launch)
• As Lead and Chair of the cross-functional global medical team
  • Responsible for representing the voice of the CPO organisation for a priority product
  • Accountable for all medical activities related to product development at the global level
  • Lead, coach, and mentor direct reports that support the global medical in development of medical brand strategy and plans, and execute and/or support execution of global tactics
  • Address broader holistic disease area considerations as they arise by convening other relevant medical leads ad-hoc
  • Play an active role within TA to articulate and implement a single, unified medical strategy across portfolio 

Enterprise Leadership:

• Maximize the positive impact for patients and GSK from early development to maturity (defined as no further significant clinical evidence generation).
• Act as a partner to the MDL and MCL, ensure integrated and thoughtful insights from across a diverse stakeholder set contribute to shaping the medicines vision, development strategy and clinical development in the early phases of development, and for refining medical strategy as clinical evidence is generated.
• Ensure that medical insights from the priority markets are incorporated into the GMT to inform all evidence, product development, and asset strategy deliverables.
• Accountable for leading the GMT in the development and delivery of the Global medical product strategy and associated global deliverables enabling prioritized LOCs to execute the strategy and deliver positive patient impact locally.
• Ensure that the evidence generation plan aligns to identified unmet needs and prioritized evidence gaps and addresses key medical and market access requirements, maximizing the asset competitiveness from launch through lifecycle management for priority markets
• Lead a global matrix team that executes on generation of evidence, publication plans and creation of content to support the priority markets to shape the practice of medicine and differentiate our medicines and vaccines.
• Act as medical Launch lead, partnering with cross-functional partners and priority markets to ensure timely and ambitious launches
• Support the cross-functional team, in partnership with the MDL and MCL for the development of ambitious LCI plans
• Lead regular assessment of medical plan impact utilizing the medical impact framework, ensuring plan reviews and proactive communication of impact measures to key stakeholders as required
• Oversee asset budget to ensure that resources are deployed against the highest the highest impact tactics
• Ensure that Global deliverables are produced on time based on market needs
• Use a Global mindset, incorporating local perspectives, to strategy development and decision making. Partner with priority markets to understand their needs and balance options to achieve the set-out goals.

Performance culture:

• Maintains the patient at the center of everything we do.
• Full immersion in the science, disease area and business to be a true and equal partner to R&D, Commercial and Key LOCs.
• Outstanding matrix leadership through the creation of a collaborative and cross-functional environment by fostering shared accountability and responsibility for delivery of specific goals and projects, and encouraging employees to work with diverse skill sets and learn from each other.
• Seek out, actively listen to and understand the needs of key markets and ensure they are appropriately reflected in the global strategy, inclusive of evidence generation and all other deliverables.
• Assess and understands the external environment, inclusive of the competitor landscape, to bring insights together to develop a clear, simple, compelling Medical strategy to improve outcomes for patients 
• Adopt a visionary and intuitive mindset, to anticipate current and future market value-drivers and evidence gaps and seek innovative solutions to them to support the long-term ambition for the asset/vaccine and its ultimate benefit for patients
• Quickly adapt to unexpected external changes, understanding impact to strategy and ability to articulate implications for both R&D and commercial
• Integrate and synthesize deep understanding of the end-to-end asset development processes, inclusive of commercialization and interconnectivities to deliver practice change and impact for patients

People:

• Be a role model to all GSK employees, setting the right tone from the top while embedding a culture of performance underpinned by GSK Purpose, strategy and culture.
• Visibly leads with authenticity and confidence to gain followship for a workable plan, even in ambiguity.
• Creates cohesion and fellowship amongst the Medical Asset/Portfolio Leadership Team, especially with key/priority LOCs, maximizing its effectiveness as a decision-making unit, external impact and fostering collective accountability for success.
• Communicates consistently and with impact, with the goal that everyone who works on an asset understands and can implement the strategy.
• Adapt approaches for seeking input and feedback to accommodate cultural differences in LOCs.
• Outstanding leader of people, directly and indirectly, creating clarity in expectations and holding oneself and team accountable
• Creates an environment where our people can develop and thrive while holding a high-performance bar across organization which he/she leads
• Identify, attract, develop and retain talent and organizational capability for the future
• Leads through uncertainty and ambiguity driving a culture of continuous improvement while building an agile learning organization

Manages corporate reputation & builds trust:

• Builds strong relationships across the enterprise to maximize synergies and impact
• Fully understands the GSK Code and relevant policies governing our work enabling team members and self to always do the right thing
• Understands and proactively identifies risk developing mitigation plans aligned to our Internal Control Framework
• Develop, gain approval for, and manage the annual budget required to deliver the objectives for in line with defined processes and policies

Qualifications

Basic

• MD/MBBS/PharmD or PhD in clinical / scientific discipline
• Experience working in medical affairs
• Experience as a respiratory biologics medical lead at the tier 1 local level or country medical director at tier 2/3 level
• Experience directing the strategy of an asset at a global level
• Experience working in respiratory or immunology
• Experience working in clinical development
• Experience of launching an asset at local and global level
• Asset lifecycle management experience at local and global level

Preferred

• Demonstrated expertise and experience in Respiratory Biologics (either clinically and/ or in pharma)
• Strong demonstration of strategic and medical leadership with scientific agility.
• Good understanding and knowledge of core principles in how to use clinical data, guide strategic use of clinical data, and understand implementation of clinical studies.
• Being the critical interaction with external experts (physicians) in the therapeutic area - requiring a high level of medical knowledge/experience, understanding of patient management, and strong clinical judgement on benefit- risk significance.
• Keeping up to date on scientific data and competitive intelligence and having the ability to transform knowledge and medical insights into patient-centred strategic thinking and transfer to action plans to drive strategies to win.
• Ability to manage ambiguity, evaluate benefit and risk and take appropriate accountability for decision making - enterprise leader with business acumen and agility to create business outputs in a VUCA (Volatility, Uncertainty, Complexity, Ambiguity) environment.
• Collaborative matrix management skills with a focus on leading diverse groups (e.g., cultural, geographical, functional) to achieve excellent results in shared goals.
• Strong financial/budget and project management skills as well as business acumen.
• Experience supporting an indication as part of a cross functional team including creation of a competitive and accessible TPP.
• General understanding of statistics, safety, regulatory requirements, including dossier preparation.
• Skilled at simultaneous consideration of scientific data and practical healthcare delivery needs from diverse health systems to optimise medical implementation of innovation.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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