Director, Technical Program Management

Posted:
3/12/2025, 7:34:56 AM

Location(s):
Massachusetts, United States ⋅ Somerville, Massachusetts, United States

Experience Level(s):
Senior

Field(s):
Product

Workplace Type:
Hybrid

About Generate:Biomedicines

Generate:Biomedicines is a new kind of therapeutics company – existing at the intersection of machine learning, biological engineering, and medicine – pioneering Generative Biology™ to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. The Company has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development.

We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!

Generate:Biomedicines was founded in 2018 by Flagship Pioneering and has received over $700 million in funding, providing the resources to rapidly scale the organization. The Company has offices in Somerville and Andover, Massachusetts with 300+ employees.

The Role: 

The Director, Technical Program Management will play a pivotal role in the development and deployment of Generate’s platform to accelerate the discovery and engineering of novel therapeutics. This leader will drive the strategic execution of engineering and research roadmaps, overseeing delivery of platform capabilities across dry and wet lab teams. 

In this role, you will lead a team of Technical Program Managers (TPMs), ensuring effective execution of cross-functional efforts while fostering a high-performing, inclusive, and collaborative environment. You will drive operational excellence by optimizing processes, influencing stakeholders, and managing risks in a dynamic and interdisciplinary setting. This role will report to the VP of Platform Strategy & Operations. 

Here's how you will contribute:

  • Lead and mentor a team of TPMs, setting clear goals, driving professional development, and establishing best practices for technical program management. 
  • Manage and scale the delivery of platform capabilities, collaborating with scientists, engineers, and cross-functional teams to define roadmaps, priorities, and scope. 
  • Serve as a strategic thought partner to team leads, ensuring alignment between scientific objectives, engineering initiatives, and overall business goals. 
  • Drive end-to-end platform development project planning and delivery, using knowledge of project methodologies including tools and techniques such as stand ups, retrospectives, etc.   
  • Navigate an ambiguous and changeable environment to track progress against goals, and anticipate and propose solutions to issues and risks  
  • Develop and manage stakeholder communications, including reporting and metrics 
  • Evaluate and improve ways of working, tools or processes for efficiency, repeatability and sustainability 
  • Foster a culture of collaboration and continuous improvement, facilitating brainstorming sessions, surfacing key themes, and streamlining complex problem-solving. 

The Ideal Candidate will have:

  • Proven experience leading and mentoring diverse TPM teams, preferably in fast-paced, high-growth environments. 
  • Extensive program management experience in Tech (AI/ML preferred) or TechBio with a strong track record of driving research and engineering initiatives to successful completion. 
  • Deep expertise in delivery of a technical platform or product, including managing dependencies across scientific, engineering, and business functions. 
  • Strong strategic and operational mindset, with the ability to define and drive complex programs while aligning stakeholders across multiple disciplines. 
  • Exceptional communication and leadership skills, with the ability to influence across all levels of an organization. 
  • Demonstrated ability to foster an inclusive and high-trust environment, building relationships with diverse stakeholders. 
  • Proactive ability to learn and acquire domain knowledge, ensuring effective partnership with ML, engineering, and scientific teams. 
  • Advanced degree preferred (or equivalent experience) in computational sciences, applied mathematics, life sciences, or a related field. 

 

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Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

COVID Safety:

Generate:Biomedicines enforces a mandatory vaccination policy for COVID-19. All employees must be fully vaccinated and have received a booster.  The purpose of this policy is to safeguard the health of our employees, their families, and the community at large from infectious disease that may be reduced by vaccinations.  The Company will make exceptions to this policy if required by applicable law and will consider requests for an exemption from this policy due to a medical reason, or because of a sincerely held religious belief, or any other exemptions that may be recognized by applicable.

Recruitment & Staffing Agencies: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto.