Alexion is AstraZeneca’s Rare Disease unit, focused on developing and delivering therapies for conditions with high unmet need, particularly those involving complement system dysregulation and select metabolic/hematologic disorders. The portfolio includes Soliris (eculizumab) and Ultomiris (ravulizumab), alongside an expanding pipeline across indications such as PNH, aHUS, generalized myasthenia gravis (gMG), and NMOSD. Alexion integrates R&D, Medical, and Commercial capabilities to advance rare disease science, accelerate patient access, and uphold rigorous standards of compliance, evidence generation, and patient-centricity. 

Position Summary

The Medical Affairs role anchors Alexion’s scientific leadership and evidence generation, ensuring patient‑centric, compliant, and data‑driven medical strategy across the product lifecycle—from launch planning to post‑marketing optimization—in collaboration with cross‑functional R&D, Regulatory, Commercial, Market Access, Quality and Safety teams.

Key Responsibilities

• Medical Strategy & Planning: Develop and execute brand medical plans, aligning scientific priorities to disease area strategy and lifecycle objectives.
• Evidence Generation: Lead or support ISR, RWE, registries, and post‑authorization studies; guide publication strategy and congress planning.
• Scientific External Engagement: Build peer‑to‑peer relationships with KOLs, patient groups, and professional societies; oversee advisory boards and medical education.
• Launch Excellence: Drive pre‑ and post‑launch activities, including data dissemination, medical training, FAQs, and response documents for rare disease audiences.
• Data Communications: Ensure high‑quality, compliant publications, field medical materials, and scientific narratives; support medical review of promotional and non‑promotional content.
• Insights & Governance: Capture medical insights to inform clinical development and strategy; uphold compliance, pharmacovigilance, and ethical standards.
• Cross‑Functional Partnership: Collaborate with Clinical Operations, Commercial, Market Access, Regulatory, Quality and Safety to define local strategy and implement local tactics.

Qualifications

• Medical Affairs experience in rare diseases, immunology/nephrology/neurology/hematology, or related areas; track record in KOL engagement, evidence generation, and launch support.
• Clinical development knowledge: Solid understanding of clinical trials, registries, and post‑authorization evidence generation.
• Regulatory and ethics awareness: Strong knowledge of local pharmaceutical regulations and associated ethical standards; committed to compliant medical practice.
• Solution‑oriented mindset: Able to navigate ambiguity and deliver outcomes in a complex, matrixed environment.
• Analytical strength: Excellent ability to interpret and synthesize medical, scientific, and technical data to inform strategy and decisions.
• Leadership: Proven ability to motivate and align cross‑functional stakeholders.
• Communication excellence: Exceptional written and verbal communication skills; proven track record of powerful presentations to diverse audiences.
• Language proficiency: Fluency in French, Dutch, and English.
• People management: Experience leading and developing medical teams (e.g.MSLs or medical advisors), including coaching, goal setting, performance management, and fostering a high‑compliance, patient‑centric culture.
• QP‑RIP accountability: Experience operating under QP‑RIP requirements (Responsible Information Pharmacist/Qualified Person for promotional information), including medical review and approval of promotional/non‑promotional materials, governance adherence, and audit readiness.

Education

• Advanced degree (MD, PharmD, PhD) in a relevant biomedical field.

Date Posted

09-Feb-2026

Closing Date

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact [email protected]. Alexion participates in E-Verify.