Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.

DESCRIPTION:

The Senior Manager, IT – Supply Chain Applications leads the strategy, implementation, and ongoing optimization of technology solutions that support end-to-end supply chain operations within a regulated life sciences environment. This role is accountable for ensuring that all systems (including ERP, Microsoft-based custom applications, and warehouse automation platforms) are GxP-compliant and aligned with corporate security and regulatory standards.

This leader will oversee a diverse global team and a technology portfolio supporting manufacturing, warehousing, and logistics functions, driving operational excellence through digital transformation, automation, and data-driven decision-making.

KEY RESPONSIBILITIES:

Strategic & Operational Leadership

• Work closely with the business develop and execute the IT roadmap for supply chain systems in alignment with business priorities and regulatory requirements.
• Collaborate closely with Operations, Quality, Regulatory Affairs, and IT leadership to ensure technology solutions meet both operational needs and compliance standards.
• Partner with global process owners to define system strategy and standardization across ERP, WMS, and automation systems.
• Champion innovation in warehouse and manufacturing automation, including robotics and data analytics, while maintaining strict adherence to validation and documentation controls.

ERP & Microsoft Application Portfolio Management

• Lead implementation, enhancement, and lifecycle management of ERP systems (e.g. Oracle) supporting supply chain and manufacturing operations.
• Oversee design and delivery of Microsoft-based applications using Azure, Power Platform and .NET technologies to extend supply chain system’s capabilities.
• Manage a structured application backlog, ensuring prioritization based on business value, regulatory impact, and resource availability.
• Establish a product-oriented delivery model aligned with Agile or hybrid methodologies suitable for regulated environments.
• Working with in-house custom built applications and their migration to off the shelf, industry standard applications
• Consolidation of application portfolio, driving simplification, operational efficiencies, and overall cost reduction Warehouse & Automation Technologies

• Direct selection, deployment, and integration of different technologies that align to the supply chain functions needs and business requirements.
• Drive continuous improvement initiatives leveraging automation and data analytics to enhance accuracy, compliance, and throughput.
• Partner with engineering, operations, and quality to maintain validated states and audit readiness for automated systems.

GxP Compliance & Computer System Validation (CSV)

• Ensure all supply chain applications and infrastructure are implemented and maintained in compliance with GxP, 21 CFR Part 11, Annex 11, and company quality system requirements.
• Promote a culture of compliance by embedding quality-by-design principles into project planning and execution.

Governance, Backlog, and Performance Management

• Own the supply chain IT governance process for prioritization, backlog management, and change control to balance compliance, innovation, and delivery speed.

Team & Vendor Leadership

• Lead a global team of IT professionals and business analysts fostering collaboration and accountability.
• Manage external partners and system integrators, ensuring compliance with company standards and quality requirements.

REQUIREMENTS:

Education & Experience

• Bachelor’s degree in computer science, Information Technology, Engineering, or a related field.
• 10+ years of IT experience in life sciences industry with 5+ years in a leadership role.
• Proven track record managing ERP implementations and enhancements in regulated environments.
• Experience with Microsoft technologies (Azure, Power Platform, .NET) in GxP-compliant contexts.
• Demonstrated expertise in 21 CFR Part 11-compliant systems.

Skills & Competencies

• Strong understanding of supply chain processes—planning, manufacturing, procurement, logistics, and distribution—in a regulated environment.
• Deep knowledge of GxP, CSV, and validation frameworks across the system lifecycle.
• Excellent leadership, stakeholder management, and communication skills.
• Demonstrated success managing product backlogs and balancing business priorities with compliance obligations.

• Ability to manage multiple priorities in a dynamic environment
• Experience with regulated environments (GMP, FDA, etc.) preferred
• Strong problem-solving and analytical capabilities
• Leadership experience in matrix organizational structures
• Change management and organizational transformation experience
• Up to 25% travel may be required

Compensation and Benefits

The salary range estimated for this position based in Pennsylvania is $130,000.00–$194,950.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

• A choice of national medical and dental plans, and a national vision plan, including health incentive programs

• Employee assistance and family support programs, including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards