Medical Director, Oncology Medical Affairs - US

Do you have expertise in, and passion for, Medical Affairs in Oncology? Would you like to apply your expertise to impact patient outcomes in the Medical Director, US Oncology Medical Affairs role at a company that follows the science and turns ideas into life-changing medicines? Then AstraZeneca might be the one for you!

About AstraZeneca

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

About the Oncology Business Unit

As a dedicated Oncology unit, this is the place to build a world-class career. Here we are always looking to learn more, welcoming the varied opportunities to expand our horizons or develop niche expertise. Embrace unparalleled access to industry-leading research, technology, and pipeline product launches with a footprint in every region. Coupled with our agility and sharp focus on talent development, there is an exciting opportunity to accelerate a rewarding and meaningful career.

Position Overview

The Medical Director is a pivotal role within the US Oncology Medical Affairs organization. Reporting directly to the Medical Head, this position is accountable for executing medical plans for specific or multiple indications within a designated disease area.

Key Accountabilities & Responsibilities

Strategic Planning & Execution

• Drive Medical Plan Development: Coordinate development of the integrated Medical Affairs Plan (iMAP), execute key projects, and track budget spend
• Lead Launch Readiness: Support Launch Readiness Reviews (LRR) by coordinating and supervising pre-launch activities, ensuring timely execution of endorsed LRR plans
• Shape Field Engagement Strategy: Synthesize field insights into practical tactics, communicate with business stakeholders, and modify plans as necessary
• Execute MALT Directives: Complete all Medical Affairs Leadership Team (MALT) initiatives as requested

Cross-Functional Collaboration

• Facilitate Quarterly Reviews: Support quarterly iMAP reviews at the Core Medical Team (CMT) in collaboration with the Medical Lead
• Review Promotional Materials: Support the Promotional Materials Review Team (PMRT) by reviewing derivative content for scientific accuracy and compliance
• Provide Cross-Functional Coverage: Support the Medical Lead on the CMT and lead working groups as appropriate

External Engagement & Stakeholder Management

• Drive Key External Expert (KEE) Engagement: Execute and monitor KEE engagement plans with follow-up to maximize engagement and impact
• Implement Advisory Boards: Independently set meeting objectives, develop discussion guides, and lead communications with vendors to execute effective Advisory Boards
• Lead Congress Activities: Plan congress activities, gather insights, manage communications, and partner with Field leadership to ensure effective pull-through at events

Evidence & Medical Education

• Oversee Evidence Reviews: Conduct evidence publication reviews and participate in Medical Education Grants Office (MEGO) selection processes
• Implement Medical Projects: Execute Medical projects while staying within scope and budget

Patient-Centricity

• Facilitate Patient Insight Sharing: Raise awareness about patient insight strategies and activities across regions, countries, and allied functions
• Build Patient Insight Capability: Work closely with Medical Affairs colleagues on research alliance initiatives, capability development programs, and tools/technology initiatives

Compliance & Ethics

• Maintain Compliance Standards: Adhere to all ethical and compliance standards as determined by the organization and/or market regulations

Essential Requirements

• Advanced Medical/Scientific Degree (Bachelor's level minimum; advanced degree strongly preferred)
• 3+ years of Medical Affairs experience in the pharmaceutical industry
• Stakeholder Management Expertise: Proven experience in relationship and stakeholder management with the 3 P's (Payers, Providers, and Patients)
• Project Management Skills: Demonstrated project and relationship management experience
• Clinical Research Knowledge: Experience with evidence generation and clinical trial methodology
• Business Acumen: Foundation knowledge in business operations and strategy
• Financial Management: Foundation knowledge in financial management and budget tracking
• Matrix Team Functionality: Specialist-level experience working effectively in matrix organizations
• Language Proficiency: Fluency in written and spoken English

Preferred Requirements

• Doctorate Degree: PharmD, MD (or equivalent) with Oncology specialization, or PhD in Sciences
• Headquarters Medical Affairs Experience: Prior experience in pharmaceutical industry headquarters Medical Affairs functions
• Technical & Regulatory Expertise: Understanding of technical, regulatory, policy, and real-world evidence generation dimensions
• Budget Management: Direct experience managing departmental or project budgets
• Strategic Planning: Experience developing and delivering country-level medical affairs plans

Why Join AstraZeneca?

At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives—and are made to feel valued, energized, and rewarded for their ideas and creativity.

Ready to make an impact in Oncology Medical Affairs? 

Apply today to join our mission of transforming patient outcomes in oncology.

The annual base pay for this position ranges from $193K to $289K. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

 

Date Posted

30-Jan-2026

Closing Date

11-Feb-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.