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A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Mahesh Yadav in the Translational Medicine Oncology department at Genentech. Dr. Yadav’s lab focuses on understanding and monitoring anti-tumor specific T cell responses to track treatment outcomes and inform clinical decisions, and discovering novel tumor antigens for cancer vaccines. This position will focus on mapping the repertoire of T cell receptors (TCRs) against tumor antigens and using this as a tool to identify and validate various classes of tumor antigens. It will also involve using advanced technologies such as single-cell sequencing (CITE-seq) and spatial transcriptomics on clinical specimens for monitoring T cell responses.  This postdoctoral position will provide an opportunity to contribute to the exciting cancer vaccine pipeline in gRED. Candidates familiar with T cell immunology, TCR sequencing, and computational analysis are especially encouraged to apply.

The Opportunity:

• Discovery and Research: Identification and mapping of antigen-specific T cells/TCRs to track longitudinal T cell dynamics

• Computational Workflow: TCR sequencing on clinical samples followed by computational analysis for identifying predictive and pharmacodynamic biomarkers  

• Collaborative Research: You will have opportunities to productively collaborate with other researchers across departments, present your work to project teams, and contribute to high-impact scientific publications.

• Strategic Impact: As a member of the Translational Medicine Oncology department, you will join leaders in leading projects that align with Genentech’s cancer vaccine strategic efforts.

• Professional Development: You will be part of the Genentech post-doctoral training program, which provides an outstanding environment and the opportunity to pursue fundamental basic science questions while utilizing clinical trial samples to drive breakthrough discoveries in drug development.

Who You Are:

• Ph.D. with a proven track record of excellence in immunology and/or cellular/ molecular biology with experience in data analysis

• Must have advanced at least one key research project as evidenced by a first author paper published or accepted in a leading peer-reviewed journal.

• Independent scientist with outstanding communication skills, a strong passion and commitment to science and immunology, who works well within a team

• Excited about identifying novel targets for treatment of cancer 

Preferred Qualifications:

• Hands-on experience in immunology/cancer immunology studies is highly desired

• Track record of successfully conducting laboratory experiments

• Working knowledge of bioinformatics tools is a plus.

Postdoc Program

Elevate your research career to new heights with Genentech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. 

The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential!

The expected salary range for this position based on the primary location of California is $100,000 to $106,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this job posting.

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