We are seeking a talented and experience neuroscientist/neuropharmacologist. This candidate will be able to demonstrate deep knowledge in CNS therapeutics for neurological disorders and psychiatric diseases. The successful candidate will be based in San Diego and work onsite and across a diverse drug discovery team and functions to influence project and company-level strategy.

Your day-to-day:

• Design and execute appropriate preclinical studies for target validation, ex vivo and in vivo target engagement.
• Collaborate across functions and with CROs to enable IVIVC & PK/PD relationship, and biomarker.
• Design appropriate studies to determine small molecule efficacy in CNS animal models.
• Establish in-house capabilities for in vivo studies to assess target engagement, PK/PD, and efficacy studies.
• Interpret, summarize, and present research findings in internal and external scientific meetings/conferences.
• Actively participate and partner with multidisciplinary drug discovery teams.
• Proactively review relevant scientific literature to contribute the newest scientific findings, ideas, methods/technologies, and target identification to the team.

Must-Haves:

• Ph.D. in cell/molecular biology, neuroscience, or pharmacology, with a minimum of 5 years industry experience.
• Experience working with various preclinical CNS disease models and understanding of model applications and limitations.
• Experience in ex vivo and in vivo CNS assays, such as neuronal cell biology/electrophysiology, neurochemistry, ex-vivo and in vivo receptor occupancy assays, and behavioral studies related to pain and psychiatric disorders.
• Understand principles of receptor pharmacology, ion channel function, synaptic physiology, brain function and CNS disorders.
• Understand biomarkers for various CNS disorders and target engagement.
• Strong record of high impact, peer reviewed publications and a proven track record of productivity and creativity.
• Capability to work within a dynamic matrix environment, with strong contribution to project strategies and progression.
• Excellent communication, presentation, and inter-personal skills; superb organizational and problem-solving skills.
• Leadership skills including decisive decision making and excellent managerial skills.
• Works well within a collaborative team, and also independently.

What makes working here great:

• Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.
• We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.
• Your perspective matters. Stick your neck out, share your ideas – we work as a team.
• We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.
• Leadership that CARES – about you, your growth + development.
• We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.
• Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!
• You get to be YOU! Show up as you are and make every day count.