Do you have extensive experience leading commercial and medical strategies in Oncology and are ready to take on a pivotal leadership role? Are you driven by the opportunity to shape the future of cancer care while working for a company that transforms scientific innovation into life-changing medicines? Then AstraZeneca is the place for you.

The Franchise Head Oncology GI is accountable for defining, adapting, and executing the franchise’s strategic vision, ensuring leadership of AstraZeneca’s oncology portfolio in priority tumor areas. This role drives sustainable growth, shapes market access, and ensures flawless execution of launches and lifecycle management, positioning Oncology as the company’s main pillar.

The incumbent leads a cross-functional team (CFT) across marketing, medical, market access, finance, regulatory, legal, compliance, PSP, and sales, ensuring strong alignment with corporate and regional oncology priorities.

Key Responsibilities

• Strategic Leadership: Define and execute the long-term franchise strategy for ovarian, prostate, and hematology, aligned with global oncology priorities.

• Cross-Functional Team Leadership: Orchestrate a multidisciplinary team (medical, marketing, market access, sales, PSP, finance, regulatory, etc.) to deliver integrated brand plans and operational excellence.

• Market Access & Policy: Partner with government affairs and access teams to influence oncology policy, secure optimal access and reimbursement, and accelerate time-to-patient.

• Brand & Portfolio Management: Oversee launches, promotional strategy, and lifecycle management, ensuring leadership positioning in competitive oncology markets.

• External Engagement: Build strong relationships with Key External Experts (KEEs), scientific societies, and patient associations to shape treatment paradigms and position AstraZeneca as the partner of choice in oncology.

• Commercial Excellence: Drive sales effectiveness through coaching, scientific engagement, and adoption of the leadership selling model.

• P&L Accountability: Ensure financial sustainability by managing budgets, demand forecasting, and profitability decisions for the oncology franchise.

• Talent & Culture: Attract, develop, and retain top oncology talent, fostering a high-performance, patient-centric culture within the franchise.

• Governance & Compliance: Safeguard compliance with company policies, ethical standards, and pharmacovigilance requirements.

Qualifications & Experience

• Proven track record of success in oncology or specialty care (minimum 10 years in commercial/medical roles, with at least 5 years in leadership).

• Demonstrated success in launching oncology products and shaping market access in complex healthcare systems.

• Strong business acumen, with experience managing P&L, strategic planning, and portfolio expansion.

• Deep knowledge of oncology market dynamics, treatment pathways, and stakeholder networks.

• Excellent leadership and stakeholder management skills, with the ability to influence at senior levels internally and externally.

• Exceptional communication, strategic thinking, and decision-making abilities in high-pressure environments.

Education

• University degree in Medicine, Pharmacy, Life Sciences, or Business-related field (advanced degree desirable).

• MBA or postgraduate studies in business, health economics, or related areas is a strong plus.

• Fluency in English required; additional languages desirable.

We invite you to apply to AstraZeneca, a company focused on being a Great Place to Work. Here, you have the opportunity to push the boundaries of science and make a meaningful impact on patients’ lives and society. We foster an inclusive, collaborative culture committed to lifelong learning, growth, and development as we continue our journey to pioneer the future of healthcare.

Date Posted

16-feb-2026

Closing Date

27-feb-2026

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.