At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue outstanding medicines in new ways, combining our people’s outstanding skills with those of people from all over the globe.

AstraZeneca holds an outstanding position in CVRM disease, with a range of differentiated medicines both on the market and in development, with an industry leading pipeline. The US Head of Early Assets, CVRM Medical is a critical strategic leadership position that reports directly to the VP Medical Cardiovascular Renal Metabolism (CVRM), within the BioPharmaceuticals Business Unit’s US Medical CVRM franchise. The candidate will work alongside their global counter parts to ensure adequate US input and involvement in our pipeline products that do not yet have dedicated local teams. This role will also work directly with local cross functional teams to build US product and disease area strategies and execution before dedicated teams are established.

What you’ll do:

• Accountable for the development and execution of disease area and brand strategies and plans for early CVRM pipeline assets
• Act as the main US source of clinical and scientific knowledge for pipeline assets’ disease area, competitive landscape, clinical pathways, and evidence gaps
• Participate proactively in global and local conversations to ensure US medical input into global and local strategies
• Partner effectively and role‑model effective teamwork across the enterprise
• Act effectively as the key US point of contact for the Global Product Team (GPT)
• Provide the US viewpoint into global clinical trial strategy and study design
• Identify, develop, and maintain positive relationships with key external and internal collaborators
• Anticipate future trends and needs in the marketplace
• Participate as part of the US Medical CVRM LT to establish a team culture that encourages continued growth and recognition
• Ensure compliance with all AstraZeneca corporate policies

Essential for the role:

• Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or equivalent education
• Medical/clinical/scientific expertise in Cardiovascular, Renal, Metabolic or related field
• 10+ years of experience in the pharmaceutical industry, ideally in Medical Affairs
• Strategic and innovative problem solver with executive presence
• Experienced team leader, with a track record of establishing high performance teams
• Proven record delivering results in a complex matrix environment, building capabilities, and leading large scale impactful medical initiatives. Experience launching a new product
• US Regulatory Strategy Knowledge/Experience, including new product approval, labeling requirements/negotiations
• Ability to flex between high level strategy and detailed tactics, as the need arises
• Confirmed ability to collaborate and build internal and external networks
• Persuasive oral and written communication skills, including the ability to develop and deliver impactful presentations
• Confirmed ability to collaborate with individuals of diverse experience and backgrounds, across varying functions, levels within the company, or external organizations, to effectively deliver on goals
• Strong intuition for business, with comprehensive understanding of the U.S. healthcare environment

Date Posted

19-Dec-2025

Closing Date

22-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.