Co-Op Assignment Overview

Prime Medicine is seeking a co-op for the Spring 2025 semester with experience in biological or chemical techniques to join the Analytical Development and QC team. The candidate will learn cutting-edge technology in the field of gene and cell therapy, obtain hands-on experience with a broad range of analytical techniques, gain understanding in  the scientific and regulatory requirements for phase appropriate analytical testing, and play a key role in solving complex technical challenges related to our prime editing strategy. This is a unique position with the opportunity to contribute directly to the advancement of prime editing programs toward the clinic. 

We want curious problem solvers who enjoy working on exciting projects, working within a team, and are passionate about developing genetic editing technologies to better human health and well-being.

Primary Responsibilities:

• Primary responsibilities will include but are not limited to, supporting the phase appropriate product development PD sample analyses, release testing, and stability studies for the characterization and release of cell and gene therapy drug products, drug substance, and critical raw materials
• Proactively seek out and explore areas for optimization, improvement in CMC or cGMP environment
• Document, present, and communicate experimental data and conclusions in an electronic notebook meeting cGMP requirement
• Collaborate with teammates across the organization and program teams to support the product and method development, method qualification.
• Adhere to all laboratory safety requirements and procedures, assist in maintaining general laboratory functionality and safety
• Flexibility in taking on new projects and troubleshooting as needs arise and priorities are dynamic
• Participate and support QC function optimization

Qualifications:

• Currently enrolled in B.S./M.S. program in Biology, Cell and Molecular Biology, Biochemistry, Bioinformatics, Biotechnology, Bioengineering, Chemical Engineering, pharmacology, or a related field
• Completion of foundational biology or chemistry coursework with a laboratory component
• Ability to work independently or collaboratively as needed
• Self-motivated, detail-oriented with strong critical thinking skills, and excels at identifying and solving technical issues
• Excellent written and verbal communication skill
• Eager to learn new knowledge or/and technical skills, GMP practic
• Comfortable engaging in cross-functional teamwork and communication
• Good organizational skills

Preferred Qualifications:

• Understanding of fundamental principles behind biological or chemical techniques, such as PCR, qPCR, ddPCR, cell analyzer, potency assay, or UV-vis, HPLC, UPLC, LC-MS, etc.
• Hand-on experience with biological or chemical analytical techniques, such as DNA/RNA extraction, PCR, enzyme digestion, cell culture or handling, sample extraction, preparation, dilution are preferred
• Knowledge and/or experience in the field of gene and cell therapy, or willingness to learn

What We Offer:

• A cutting-edge team open to mentorship and networking.
• Full reimbursement for monthly commuting costs including MBTA, Commuter Rail, or Bluebikes, etc.
• Participation in regular seminars with industry experts.
• Full participation in employee activities including learning and development offerings, social activities, etc.

NOTE: We are currently not considering co-op candidates outside of the local Boston/Cambridge area.